HLAI |
Blood & Marrow Transplant |
Buccal Swab DNA Isolation for High Resolution Testing |
Isolation of highly purified DNA from a buccal swab sample for high resolution testing
|
NA |
Buccal swab |
81479x2 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
Buccal Swab DNA Isolation for Low/Intermediate Resolution |
Isolation of highly purified DNA from a buccal swab sample for low to intermediate resolution testing
|
NA |
Buccal swab |
81479 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
CD3 |
Determination of absolute count & percentage of CD3 T lymphocytes in peripheral blood or apheresis product for subsequent donor leukocyte infusion by flow cytometry
|
3 hours from sample receipt, when lab notified in advance |
Samples must be received within 24 hours of collection. EDTA 3mL of anticoagulated whole blood; EDTA 0.5mL of pheresis unit, cord blood or bone marrow anticoagulated |
86359, 88184, 88185, 88187 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
Chimerism Studies |
Testing of post transplant blood samples for percentage mixture of donor and patient DNA
|
3-5 Business Days |
Pre-transplant DNA from recipient and donor; Post-transplant sample from recipient; 5-7 mL EDTA |
81267 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI (A,B,C,DR,DQ) HR for Patient or unrelated Donor Typing to include DRB3/4/5 |
Sequenced Based Typing (SBT) and/or DNA based assay for HLAI A, B C, DR and DQ alleles provides a high resolution HLAI phenotype for new transplant patients and their potential unrelated donors
|
7±2 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 - 1ml; Buccal swabs are acceptable |
81379, 81382x3 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI (A,B,C) Supplemental HR |
DNA based assay provides high resolution (4 digits) typing of HLAI A,B,C alleles following preliminary HLAI (A,B,DR) IR typing of transplant patient siblings
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81379 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI (A,B,DR) IR |
DNA based assay provides initial intermediate resolution (2 digits) typing of HLAI A, B, DR for preliminary assessment of histocompatibility in siblings of transplant recipient
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 - 1ml; Buccal swabs are acceptable |
81371 |
HLAI Requisition Form BS 320H |
HLAI |
Blood Donor Typing, Platelet Refractory Panel |
HLAI (A,B) IR for Apheresis Platelet Donors |
DNA based assay provides intermediate resolution (2 digits) of HLAI-A,B alleles. Typing apheresis donor is required prior to donating for HLAI matched platelets.
|
21-30 business days |
5-7 mL EDTA; shipped within 7 days of collection |
81373x2 |
HLAI Requisition Form BS 320H |
HLAI, IRL |
Platelet Refractory Panel, Platelet Testing |
HLAI (A,B) IR for Patient Platelet Transfusions |
DNA based assay provides intermediate resolution (2 digits) typing of HLAI-A,B alleles. Typing required for patient before search for HLAI matched platelets.
|
48 hours |
Adults: 10-20 mL EDTA; Adults WBC <4x10^6/mL or 4000/µL: 20-40 mL EDTA; Pediatrics: Consult with laboratory |
81373x2 |
Form BS 313, HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI (DR,DQ) Supplemental HR to include DRB3/4/5 |
DNA based assay provides high resolution (4 digits) typing to determine phenotype for selected siblings of transplant recipient
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81382x3 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI A, Supplemental HR |
DNA based assay provides high resolution (4 digits) typing of HLAI A alleles with previous LR results
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA |
81380 |
HLAI Requisition Form BS 320H |
HLAI, IRL |
HLAI Class I & II Antibody Screen and ID, Platelet Refractory Panel |
HLAI Antibody ID Class I |
Identification of antibody specificities to HLAI Class I (A,B,C) antigens by Luminex microbead array methodology
|
3 business days |
10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw |
86832 |
Form BS 313, HLAI Requisition Form BS 320H |
HLAI |
HLAI Class I & II Antibody Screen and ID |
HLAI Antibody ID Class II |
Identification of antibody specificities to HLAI Class II (DR,DQ,DP) antigens by Luminex microbead array methodology
|
3 business days |
10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw |
86833 |
Form BS 313, HLAI Requisition Form BS 320H |
HLAI, IRL |
HLAI Class I & II Antibody Screen and ID, Platelet Refractory Panel |
HLAI Antibody Screen |
Screen for antibodies to HLAI Class I (A,B,C) and Class II (DR,DQ,DP) and MIC antigens by Luminex microbead array methodology
|
3 business days |
10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw |
86828 |
Form BS 313, HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI B, Supplemental HR |
DNA based assay to provide high resolution (4 digits) typing of HLAI B alleles with previous LR results
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA |
81380 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI C, Supplemental HR |
DNA based assay to provide high resolution (4 digits) typing of HLAI C alleles with previous LR results
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA |
81380 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Class I (A,B,C) HR |
DNA based assay used to achieve definition at high resolution (4 digits) of Class I HLAI-A,B,C alleles
|
7±2 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81379 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Class I (A,B,C) IR |
DNA based assay provides low to intermediate resolution (2 digits) assignment of Class I HLAI-A,B,C alleles
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81372 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Class I Single Locus IR (e.g. B*27) |
DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes
|
7-10 Business Days |
5-10mL EDTA |
81373 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Class II (DR,DQ) HR to include DRB3/4/5 |
DNA based assay provides high resolution (4 digits) typing of HLAI DRB1, DRB3/4/5 and DQB1 alleles following preliminary HLAI (A,B,DR) IR typing of transplant patient siblings
|
7±2 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81382x3 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Class II (DR,DQ) IR |
DNA based assay provides low to intermediate resolution (2 digits) assignment of Class II HLAI DR, DQ alleles.
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81375 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Class II Single Locus IR (e.g. DQ2, DQ8) |
DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes
|
7-10 Business Days |
5-10mL EDTA |
81376 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI DPA1 HR |
DNA based assay to provide high resolution (4 digits) typing of HLAI DPA1 alleles
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81382 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI DPB1 HR |
DNA based assay to provide high resolution (4 digits) typing of HLAI DPB1 alleles
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81382 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI DQA1 HR |
DNA based assay to provide high resolution (4 digits) typing of HLAI DQA1 alleles
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable |
81382 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI DQB1 Supplemental HR |
DNA based assay provides high resolution (4 digits) typing of HLAI DQB1 alleles with previous LR results
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA |
81382 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI DRB1 Supplemental HR |
DNA based assay provides high resolution (4 digits) typing of HLAI DRB1 alleles with previous LR results
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA |
81382 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI DRB3/4/5 Supplemental HR |
DNA based assay provides high resolution (4 digits) typing of HLAI DRB3/4/5 alleles with previous LR results
|
5-7 Business Days |
Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA |
81382 |
HLAI Requisition Form BS 320H |
HLAI, IRL |
Platelet Refractory Panel |
HLAI Matched Platelet Pheresis Donor Search |
Search of maintained registry of previously HLAI typed donors to identify suitably HLAI matched or compatible platelet pheresis donors for patients who are refractory to random donor platelets due to HLAI antibodies. For patients that have previously completed HLAI A,B typing or concurrent orders for HLAI typing.
|
Same Day |
NA |
99090 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI Priority Services |
Reduced reporting time arranged by lab supervisor
|
NA |
NA |
99051 |
HLAI Requisition Form BS 320H |
HLAI |
Blood & Marrow Transplant |
HLAI STAT After Hours |
Reduced reporting time arranged by lab supervisor
|
NA |
NA |
99050 |
HLAI Requisition Form BS 320H |
HLAI, IRL |
Platelet Refractory Panel, Platelet Testing |
Platelet Antibody Detection |
The Capture-P Ready Screen Solid Phase System is designed to detect IgG- HPA and -HLAI antibodies. The assay does NOT differentiate between HLAI or HPA antibodies. The assay is not designed to detect complement components or antibodies of the IgM or IgA class.
|
Depends upon request; See TAT description |
3-7 mL EDTA (plasma) or serum tube (no gel separators).
Sample must be received in the IRL no later than 30 hrs after collection.
Shipped in a container maintaining temperature between 1C - 10C |
86022 |
Form BS 313 |
HLAI, IRL |
Platelet Refractory Panel |
Platelet Refractory Panel |
Platelet antibody screen and crossmatch, HLAI A,B typing, HLAI matched platelet donor search, HLAI antibody screen (if positive, HLAI antibody identification Class I)
|
48 hours |
Three EDTA whole blood, and 5-7 mL clot (serum) tube (no gel separators). Sample must be received in the IRL no later than 30 hrs after collection. Icteric, hemolyzed and/or lipemic samples interfere with test and should not be tested as per package insert. Shipped in a container maintaining temperature between 1C - 10C |
99090 |
Form BS 313, HLAI Requisition Form BS 320H |