Test Categories: Blood & Marrow Transplant

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Laboratory Category Test Name Description Turn Around Times Sample, Packaging & Shipping Requirements Form
HLA Blood & Marrow Transplant Buccal Swab DNA Isolation for High Resolution Testing Isolation of highly purified DNA from a buccal swab sample for high resolution testing NA Buccal swab HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant Buccal Swab DNA Isolation for Low/Intermediate Resolution Isolation of highly purified DNA from a buccal swab sample for low to intermediate resolution testing NA Buccal swab HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant CD3 Determination of absolute count & percentage of CD3 T lymphocytes in peripheral blood or apheresis product for subsequent donor leukocyte infusion by flow cytometry 3 hours from sample receipt, when lab notified in advance Samples must be received within 24 hours of collection. EDTA 3mL of anticoagulated whole blood; EDTA 0.5mL of pheresis unit, cord blood or bone marrow anticoagulated HLA Requisition Form BS 320H
CTL Blood & Marrow Transplant CD34 Enumeration with Viability Determination of absolute count, percentage, and viability of CD34 progenitor cells in peripheral blood, pheresis product or bone marrow by flow cytometry 2 hours from sample receipt, when lab notified in advance Samples must be received within 24 hours of collection. EDTA 3mL of anticoagulated whole blood; EDTA 0.5mL of pheresis unit, cord blood or bone marrow anticoagulated CTL Requisition Form HPP 203
HLA Blood & Marrow Transplant Chimerism Studies Testing of post transplant blood samples for percentage mixture of donor and patient DNA 3-5 Business Days Pre-transplant DNA from recipient and donor; Post-transplant sample from recipient; 5-7 mL EDTA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA (A,B,C,DR,DQ) HR for Patient or unrelated Donor Typing to include DRB3/4/5 Sequenced Based Typing (SBT) and/or DNA based assay for HLA A, B C, DR and DQ alleles provides a high-resolution HLA phenotype for new transplant patients and their potential unrelated donors 7±2 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 - 1ml; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA (A,B,C) Supplemental HR DNA based assay provides high resolution (4 digits) typing of HLA A,B,C alleles following preliminary HLA (A,B,DR) IR typing of transplant patient siblings 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA (A,B,DR) IR DNA based assay provides initial intermediate resolution (2 digits) typing of HLA A, B, DR for preliminary assessment of histocompatibility in siblings of transplant recipient 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 - 1ml; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA (DR,DQ) Supplemental HR to include DRB3/4/5 DNA based assay provides high resolution (4 digits) typing to determine phenotype for selected siblings of transplant recipient 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA A, Supplemental HR DNA based assay provides high resolution (4 digits) typing of HLA A alleles with previous LR results 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA B, Supplemental HR DNA based assay to provide high resolution (4 digits) typing of HLA B alleles with previous LR results 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA C, Supplemental HR DNA based assay to provide high resolution (4 digits) typing of HLA C alleles with previous LR results 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Class I (A,B,C) HR DNA based assay used to achieve definition at high resolution (4 digits) of Class I HLA-A,B,C alleles 7±2 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Class I (A,B,C) IR DNA based assay provides low to intermediate resolution (2 digits) assignment of Class I HLA-A,B,C alleles 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Class I Single Locus IR (e.g. B*27) DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes 7-10 Business Days 5-10mL EDTA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Class II (DR,DQ) HR to include DRB3/4/5 DNA based assay provides high resolution (4 digits) typing of HLA DRB1, DRB3/4/5 and DQB1 alleles following preliminary HLA (A,B,DR) IR typing of transplant patient siblings 7±2 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Class II (DR,DQ) IR DNA based assay provides low to intermediate resolution (2 digits) assignment of Class II HLA DR, DQ alleles. 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Class II Single Locus IR (e.g. DQ2, DQ8) DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes 7-10 Business Days 5-10mL EDTA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA DPA1 HR DNA based assay to provide high resolution (4 digits) typing of HLA DPA1 alleles 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA DPB1 HR DNA based assay to provide high resolution (4 digits) typing of HLA DPB1 alleles 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA DQA1 HR DNA based assay to provide high resolution (4 digits) typing of HLA DQA1 alleles 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA DQB1 Supplemental HR DNA based assay provides high resolution (4 digits) typing of HLA DQB1 alleles with previous LR results 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA DRB1 Supplemental HR DNA based assay provides high resolution (4 digits) typing of HLA DRB1 alleles with previous LR results 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA DRB3/4/5 Supplemental HR DNA based assay provides high resolution (4 digits) typing of HLA DRB3/4/5 alleles with previous LR results 5-7 Business Days Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA Priority Services Reduced reporting time arranged by lab supervisor NA NA HLA Requisition Form BS 320H
HLA Blood & Marrow Transplant HLA STAT After Hours Reduced reporting time arranged by lab supervisor NA NA HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name Buccal Swab DNA Isolation for High Resolution Testing
Description Isolation of highly purified DNA from a buccal swab sample for high resolution testing
Turn Around Times NA
Sample, Packaging & Shipping Requirements Buccal swab
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name Buccal Swab DNA Isolation for Low/Intermediate Resolution
Description Isolation of highly purified DNA from a buccal swab sample for low to intermediate resolution testing
Turn Around Times NA
Sample, Packaging & Shipping Requirements Buccal swab
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name CD3
Description Determination of absolute count & percentage of CD3 T lymphocytes in peripheral blood or apheresis product for subsequent donor leukocyte infusion by flow cytometry
Turn Around Times 3 hours from sample receipt, when lab notified in advance
Sample, Packaging & Shipping Requirements Samples must be received within 24 hours of collection. EDTA 3mL of anticoagulated whole blood; EDTA 0.5mL of pheresis unit, cord blood or bone marrow anticoagulated
Form HLA Requisition Form BS 320H
Laboratory CTL
Category Blood & Marrow Transplant
Test Name CD34 Enumeration with Viability
Description Determination of absolute count, percentage, and viability of CD34 progenitor cells in peripheral blood, pheresis product or bone marrow by flow cytometry
Turn Around Times 2 hours from sample receipt, when lab notified in advance
Sample, Packaging & Shipping Requirements Samples must be received within 24 hours of collection. EDTA 3mL of anticoagulated whole blood; EDTA 0.5mL of pheresis unit, cord blood or bone marrow anticoagulated
Form CTL Requisition Form HPP 203
Laboratory HLA
Category Blood & Marrow Transplant
Test Name Chimerism Studies
Description Testing of post transplant blood samples for percentage mixture of donor and patient DNA
Turn Around Times 3-5 Business Days
Sample, Packaging & Shipping Requirements Pre-transplant DNA from recipient and donor; Post-transplant sample from recipient; 5-7 mL EDTA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA (A,B,C,DR,DQ) HR for Patient or unrelated Donor Typing to include DRB3/4/5
Description Sequenced Based Typing (SBT) and/or DNA based assay for HLA A, B C, DR and DQ alleles provides a high-resolution HLA phenotype for new transplant patients and their potential unrelated donors
Turn Around Times 7±2 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 - 1ml; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA (A,B,C) Supplemental HR
Description DNA based assay provides high resolution (4 digits) typing of HLA A,B,C alleles following preliminary HLA (A,B,DR) IR typing of transplant patient siblings
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA (A,B,DR) IR
Description DNA based assay provides initial intermediate resolution (2 digits) typing of HLA A, B, DR for preliminary assessment of histocompatibility in siblings of transplant recipient
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Cord blood sample: 0.5 - 1ml; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA (DR,DQ) Supplemental HR to include DRB3/4/5
Description DNA based assay provides high resolution (4 digits) typing to determine phenotype for selected siblings of transplant recipient
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA A, Supplemental HR
Description DNA based assay provides high resolution (4 digits) typing of HLA A alleles with previous LR results
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA B, Supplemental HR
Description DNA based assay to provide high resolution (4 digits) typing of HLA B alleles with previous LR results
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA C, Supplemental HR
Description DNA based assay to provide high resolution (4 digits) typing of HLA C alleles with previous LR results
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Class I (A,B,C) HR
Description DNA based assay used to achieve definition at high resolution (4 digits) of Class I HLA-A,B,C alleles
Turn Around Times 7±2 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Class I (A,B,C) IR
Description DNA based assay provides low to intermediate resolution (2 digits) assignment of Class I HLA-A,B,C alleles
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Class I Single Locus IR (e.g. B*27)
Description DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes
Turn Around Times 7-10 Business Days
Sample, Packaging & Shipping Requirements 5-10mL EDTA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Class II (DR,DQ) HR to include DRB3/4/5
Description DNA based assay provides high resolution (4 digits) typing of HLA DRB1, DRB3/4/5 and DQB1 alleles following preliminary HLA (A,B,DR) IR typing of transplant patient siblings
Turn Around Times 7±2 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Class II (DR,DQ) IR
Description DNA based assay provides low to intermediate resolution (2 digits) assignment of Class II HLA DR, DQ alleles.
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Class II Single Locus IR (e.g. DQ2, DQ8)
Description DNA based typing of any single locus provides intermediate resolution (2 digits) typing to determine presence or absence of 1 or 2 antigens/alleles named by client for disease association or research purposes
Turn Around Times 7-10 Business Days
Sample, Packaging & Shipping Requirements 5-10mL EDTA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA DPA1 HR
Description DNA based assay to provide high resolution (4 digits) typing of HLA DPA1 alleles
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA DPB1 HR
Description DNA based assay to provide high resolution (4 digits) typing of HLA DPB1 alleles
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA DQA1 HR
Description DNA based assay to provide high resolution (4 digits) typing of HLA DQA1 alleles
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA DQB1 Supplemental HR
Description DNA based assay provides high resolution (4 digits) typing of HLA DQB1 alleles with previous LR results
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA DRB1 Supplemental HR
Description DNA based assay provides high resolution (4 digits) typing of HLA DRB1 alleles with previous LR results
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA DRB3/4/5 Supplemental HR
Description DNA based assay provides high resolution (4 digits) typing of HLA DRB3/4/5 alleles with previous LR results
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Adults (normal WBC): 10-20 mL EDTA; Pediatrics: 3-7 mL EDTA or anticoagulated whole blood, depending on age of child; Buccal swabs are acceptable or frozen DNA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA Priority Services
Description Reduced reporting time arranged by lab supervisor
Turn Around Times NA
Sample, Packaging & Shipping Requirements NA
Form HLA Requisition Form BS 320H
Laboratory HLA
Category Blood & Marrow Transplant
Test Name HLA STAT After Hours
Description Reduced reporting time arranged by lab supervisor
Turn Around Times NA
Sample, Packaging & Shipping Requirements NA
Form HLA Requisition Form BS 320H