Immunohematology Reference Laboratory

At our immunohematology reference laboratories (IRLs), we have the coveted combination of talent, expertise and rare reagents to deliver definitive results. Our services give you and your clinicians the confidence to move forward in providing transfusion therapy to your patients.

Our talented staff have a unique combination of experience and education to partner with you for your continuing education needs, offering lectures or workshops on a variety of Transfusion Medicine topics.

With our state-of-the-art equipment, experienced technical team and proximity to transportation hubs for ultra-reliable receiving, Vitalant is the provider of choice for hospital transfusion services from all over the U.S. for:

  • Basic to complex red cell serological testing using multiple testing platforms
  • Molecular genetic testing for erythrocytes and platelets
  • Antigen negative blood products
  • Platelet antibody screening
  • Platelet crossmatching
  • HLA matched platelets

For technical or clinical consultations, please see Contact Us for desired location.

Contact us to discuss any of our tests or services.

Indicate on the IRL order form if samples are for a patient who is receiving or who is scheduled to receive daratumumab (i.e. DARZALEX™ or DARA) anti-CD38 therapy for multiple myeloma.

IRL
HLA
CTL
TS
BS 313

BS 320H

TS 003
Laboratory Category Test Name Description Turn Around Times Sample, Packaging & Shipping Requirements Form
IRL Red Cell Serology 4C Antibody Identification Test for identification of antibodies reactive best at 4C Depends upon request; See TAT description 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology ABO Discrepancy (includes A2 cells & anti-A,B) Resolution of ABO blood group typing discrepancies Depends upon request; See TAT description 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology ABO Grouping ABO blood group typing Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Adsorption Autoadsorption using patient’s own cells or allogeneic adsorption using reagent red cells of known phenotype Depends upon request; See TAT description 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL, Transfusion Service Compatibility Testing & Product Services, Red Cell Serology Antibody Detection (screen) Red cell antibody screen by multiple methodologies Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL, Transfusion Service Compatibility Testing & Product Services, Red Cell Serology Antibody Identification Panel Red cell antibody identification by multiple methodologies Depends upon request; See TAT description 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Antibody Screen – Gel Red cell antibody screen by gel technology Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Antigen Typing, Donation (per antigen) Donor blood typing for common antigens (serological) Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Antigen Typing, Patient (per antigen) Patient blood typing for common antigens (serological) Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Antigen Typing, Rare-Donation (per antigen) Donor blood typing for rare antigens (serological) Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Antigen Typing, Rare-Patient (per antigen) Patient blood typing for rare antigens (serological) Depends upon request; See TAT description 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Cold Agglutinin Screen Test for detection of antibodies reactive best at 4C Depends upon request; See TAT description Serum/plasma collected and separated at 37 C and 1 EDTA. Please contact the IRL.
IRL Red Cell Serology Cold Agglutinin Titer To provide instructions for determining the titer of cold reactive autoantibody for cases in which cold agglutinin disease is suspected. Depends upon request; See TAT description Serum or plasma separated from freshly collected blood; sample maintained at 37C; minimum volume 2mL
IRL Red Cell Serology Computer Unit Search Computer search of the Vitalant inventory for specifically typed products 2 hours NA
IRL Red Cell Serology Direct Antiglobulin Test (DAT) (per test) The direct antiglobulin test is used to demonstrate antibodies and/or complement bound to the red cells “in-vivo”. Depends upon request; See TAT description 1 EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Donath-Landsteiner Test Diagnostic test for Paroxysmal Cold Hemoglobinuria (PCH) Depends upon request; See TAT description Serum collected and separated at 37 C and 1 EDTA. Please contact the IRL.
IRL Red Cell Serology Drug Dependent Antibody Studies Tests for identification of drug dependent antibodies Depends upon request; See TAT description 2 large EDTA or red top tubes; sample of drug under investigation, in the same form (tablet, solution, capsules) that the patient is receiving
IRL Red Cell Serology Elution Removal of antibody from red cells for further identification testing Depends upon request; See TAT description 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Enzyme Treatment Panel Premodification of red blood cells using proteolytic enzymes (i.e. Ficin, Papain, etc.) Depends upon request; See TAT description NA
IRL Red Cell Serology Extended Phenotype Patient typing for common blood group antigens, excluding Rh Depends upon request; See TAT description 1 EDTA tube ; Shipped in a container maintaining temperature between 1C - 10 C
HLA, IRL Platelet Refractory Panel, Platelet Testing HLA (A,B) IR for Patient Platelet Transfusions DNA based assay provides intermediate resolution (2 digits) typing of HLA-A,B alleles. Typing required for patient before search for HLA matched platelets. 48 hours Adults: 10-20 mL EDTA; Adults WBC <4x10^6/mL or 4000/µL: 20-40 mL EDTA; Pediatrics: Consult with laboratory
HLA, IRL HLA Class I & II Antibody Screen and ID, Platelet Refractory Panel HLA Antibody ID Class I Identification of antibody specificities to HLA Class I (A,B,C) antigens by Luminex microbead array methodology 3 business days 10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw
HLA, IRL HLA Class I & II Antibody Screen and ID, Platelet Refractory Panel HLA Antibody Screen Screen for antibodies to HLA Class I (A,B,C) and Class II (DR,DQ,DP) and MIC antigens by Luminex microbead array methodology 3 business days 10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw
HLA, IRL Platelet Refractory Panel HLA Matched Platelet Pheresis Donor Search Search of maintained registry of previously HLA typed donors to identify suitably HLA matched or compatible platelet pheresis donors for patients who are refractory to random donor platelets due to HLA antibodies. For patients that have previously completed HLA A,B typing or concurrent orders for HLA typing. Same Day NA
IRL Red Cell Serology Lectin Study Diagnostic test for polyagglutination Depends upon request; See TAT description 1 EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Blood Donor Typing, Molecular Testing (DNA Genotyping) Molecular Platelet Genotyping (HPA) – Donor Molecular determination of 11 allelic variants that determine common Human Platelet Antigens, using multiplex PCR and microarray analysis. Includes DNA extraction and purification. 5-7 Business Days 1 EDTA ( 7mL) tube
IRL Molecular Testing (DNA Genotyping), Platelet Testing Molecular Platelet Genotyping (HPA) – Patient Molecular determination of 11 allelic variants that determine common Human Platelet Antigens, using multiplex PCR and microarray analysis. Includes DNA extraction and purification. 5-7 Business Days 2 EDTA (7 mL) tubes
IRL Blood Donor Typing, Molecular Testing (DNA Genotyping) Molecular Red Cell Genotyping (HEA) – Donor Molecular determination of 38 allelic variants that determine common and rare red cell antigens plus hemoglobin S status, using multiplex PCR and microarray analysis. Includes DNA extraction and purification. 5-7 Business Days Business Days 1 EDTA ( 7mL) tube
IRL Molecular Testing (DNA Genotyping) Molecular Red Cell Genotyping (HEA) – Patient Molecular determination of 38 allelic variants that determine common and rare red cell antigens plus hemoglobin S status, using multiplex PCR and microarray analysis. Includes DNA extraction and purification. 5-7 Business Days 2 EDTA (7 mL) tubes
HLA, IRL Platelet Refractory Panel, Platelet Testing Platelet Antibody Detection The Capture-P Ready Screen Solid Phase System is designed to detect IgG- HPA and -HLA antibodies. The assay does NOT differentiate between HLA or HPA antibodies. The assay is not designed to detect complement components or antibodies of the IgM or IgA class. Depends upon request; See TAT description 3-7 mL EDTA (plasma) or serum tube (no gel separators). Sample must be received in the IRL no later than 30 hrs after collection. Shipped in a container maintaining temperature between 1C - 10C
IRL Platelet Refractory Panel, Platelet Testing Platelet Crossmatch – SP The Capture-P Solid Phase System is designed to detect IgG HPA and HLA antibodies. The assay is not designed to detect complement components or antibodies of the IgM or IgA class. Depends upon request; See TAT description 3-7 mL EDTA (plasma) or serum (not from gel separator tubes). ; Must be received within 30 hours of collection. ; Shipper to maintain temperature between 1C - 10C
HLA, IRL Platelet Refractory Panel Platelet Refractory Panel Platelet antibody screen and crossmatch, HLA A,B typing, HLA matched platelet donor search, HLA antibody screen (if positive, HLA antibody identification Class I) 48 hours Three EDTA whole blood, and 5-7 mL clot (serum) tube (no gel separators). Sample must be received in the IRL no later than 30 hrs after collection. Icteric, hemolyzed and/or lipemic samples interfere with test and should not be tested as per package insert. Shipped in a container maintaining temperature between 1C - 10C
IRL Red Cell Serology Red Cell Separation Separation of patient red cells from transfused red cells Depends upon request; See TAT description 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Red Cell Treatment – EGA/CHL/DTT Chemical premodification of red cells for testing Depends upon request; See TAT description 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Rh (D) Typing Rh (D) typing of red cells Depends upon request; See TAT description 1 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Rh Discrepancy Resolution of typing discrepancy Depends upon request; See TAT description 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Rh Phenotype Common Rh antigen phenotyping, excluding Rh (D) Depends upon request; See TAT description 1 EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Special Serum Studies (0.01 M DTT, others) Selective inactivation of IgM class immunoglobulin Depends upon request; See TAT description 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Special Serum Studies (Neutralization/Inhibition, i.e. Le & P1 substance) Antibody inhibition using blood group substances Depends upon request; See TAT description 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Thermal Amplitude Determination of optimal temperature of reactivity of cold antibodies 24 hours Serum collected and separated at 37 C and 1 EDTA. Please contact the IRL.
IRL Red Cell Serology Titration Studies (per titration) Serial dilution of the sample and testing NA 1 plain red top and 1 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
IRL Red Cell Serology Turn Around Times STAT: 8 hours; ASAP: 24 hours; Routine: 1-2 days Depends upon request; See TAT description Insufficient sample or incomplete patient information may result in delays
Laboratory IRL
Category Red Cell Serology
Test Name 4C Antibody Identification
Description Test for identification of antibodies reactive best at 4C
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name ABO Discrepancy (includes A2 cells & anti-A,B)
Description Resolution of ABO blood group typing discrepancies
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name ABO Grouping
Description ABO blood group typing
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Adsorption
Description Autoadsorption using patient’s own cells or allogeneic adsorption using reagent red cells of known phenotype
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL, Transfusion Service
Category Compatibility Testing & Product Services, Red Cell Serology
Test Name Antibody Detection (screen)
Description Red cell antibody screen by multiple methodologies
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313, Transfusion Services Order Form TS 003
Laboratory IRL, Transfusion Service
Category Compatibility Testing & Product Services, Red Cell Serology
Test Name Antibody Identification Panel
Description Red cell antibody identification by multiple methodologies
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313, Transfusion Services Order Form TS 003
Laboratory IRL
Category Red Cell Serology
Test Name Antibody Screen – Gel
Description Red cell antibody screen by gel technology
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Antigen Typing, Donation (per antigen)
Description Donor blood typing for common antigens (serological)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Antigen Typing, Patient (per antigen)
Description Patient blood typing for common antigens (serological)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Antigen Typing, Rare-Donation (per antigen)
Description Donor blood typing for rare antigens (serological)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Antigen Typing, Rare-Patient (per antigen)
Description Patient blood typing for rare antigens (serological)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and/or EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Cold Agglutinin Screen
Description Test for detection of antibodies reactive best at 4C
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements Serum/plasma collected and separated at 37 C and 1 EDTA. Please contact the IRL.
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Cold Agglutinin Titer
Description To provide instructions for determining the titer of cold reactive autoantibody for cases in which cold agglutinin disease is suspected.
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements Serum or plasma separated from freshly collected blood; sample maintained at 37C; minimum volume 2mL
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Computer Unit Search
Description Computer search of the Vitalant inventory for specifically typed products
Turn Around Times 2 hours
Sample, Packaging & Shipping Requirements NA
Form Contact IRL Laboratory
Laboratory IRL
Category Red Cell Serology
Test Name Direct Antiglobulin Test (DAT) (per test)
Description The direct antiglobulin test is used to demonstrate antibodies and/or complement bound to the red cells “in-vivo”.
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Donath-Landsteiner Test
Description Diagnostic test for Paroxysmal Cold Hemoglobinuria (PCH)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements Serum collected and separated at 37 C and 1 EDTA. Please contact the IRL.
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Drug Dependent Antibody Studies
Description Tests for identification of drug dependent antibodies
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 2 large EDTA or red top tubes; sample of drug under investigation, in the same form (tablet, solution, capsules) that the patient is receiving
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Elution
Description Removal of antibody from red cells for further identification testing
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Enzyme Treatment Panel
Description Premodification of red blood cells using proteolytic enzymes (i.e. Ficin, Papain, etc.)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements NA
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Extended Phenotype
Description Patient typing for common blood group antigens, excluding Rh
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 EDTA tube ; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory HLA, IRL
Category Platelet Refractory Panel, Platelet Testing
Test Name HLA (A,B) IR for Patient Platelet Transfusions
Description DNA based assay provides intermediate resolution (2 digits) typing of HLA-A,B alleles. Typing required for patient before search for HLA matched platelets.
Turn Around Times 48 hours
Sample, Packaging & Shipping Requirements Adults: 10-20 mL EDTA; Adults WBC <4x10^6/mL or 4000/µL: 20-40 mL EDTA; Pediatrics: Consult with laboratory
Form Form BS 313, HLA Requisition Form BS 320H
Laboratory HLA, IRL
Category HLA Class I & II Antibody Screen and ID, Platelet Refractory Panel
Test Name HLA Antibody ID Class I
Description Identification of antibody specificities to HLA Class I (A,B,C) antigens by Luminex microbead array methodology
Turn Around Times 3 business days
Sample, Packaging & Shipping Requirements 10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw
Form Form BS 313, HLA Requisition Form BS 320H
Laboratory HLA, IRL
Category HLA Class I & II Antibody Screen and ID, Platelet Refractory Panel
Test Name HLA Antibody Screen
Description Screen for antibodies to HLA Class I (A,B,C) and Class II (DR,DQ,DP) and MIC antigens by Luminex microbead array methodology
Turn Around Times 3 business days
Sample, Packaging & Shipping Requirements 10 mL clotted whole blood in red top tube; blood specimens may be kept at room temperature and shipped at room temp or 24C up to 4 days after collection; OR separated serum from clot tube may be refrigerated at 4C and shipped up to 7 days from date of draw
Form Form BS 313, HLA Requisition Form BS 320H
Laboratory HLA, IRL
Category Platelet Refractory Panel
Test Name HLA Matched Platelet Pheresis Donor Search
Description Search of maintained registry of previously HLA typed donors to identify suitably HLA matched or compatible platelet pheresis donors for patients who are refractory to random donor platelets due to HLA antibodies. For patients that have previously completed HLA A,B typing or concurrent orders for HLA typing.
Turn Around Times Same Day
Sample, Packaging & Shipping Requirements NA
Form HLA Requisition Form BS 320H
Laboratory IRL
Category Red Cell Serology
Test Name Lectin Study
Description Diagnostic test for polyagglutination
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Blood Donor Typing, Molecular Testing (DNA Genotyping)
Test Name Molecular Platelet Genotyping (HPA) – Donor
Description Molecular determination of 11 allelic variants that determine common Human Platelet Antigens, using multiplex PCR and microarray analysis. Includes DNA extraction and purification.
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements 1 EDTA ( 7mL) tube
Form Form BS 313
Laboratory IRL
Category Molecular Testing (DNA Genotyping), Platelet Testing
Test Name Molecular Platelet Genotyping (HPA) – Patient
Description Molecular determination of 11 allelic variants that determine common Human Platelet Antigens, using multiplex PCR and microarray analysis. Includes DNA extraction and purification.
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements 2 EDTA (7 mL) tubes
Form Form BS 313
Laboratory IRL
Category Blood Donor Typing, Molecular Testing (DNA Genotyping)
Test Name Molecular Red Cell Genotyping (HEA) – Donor
Description Molecular determination of 38 allelic variants that determine common and rare red cell antigens plus hemoglobin S status, using multiplex PCR and microarray analysis. Includes DNA extraction and purification.
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements Business Days 1 EDTA ( 7mL) tube
Form Form BS 313
Laboratory IRL
Category Molecular Testing (DNA Genotyping)
Test Name Molecular Red Cell Genotyping (HEA) – Patient
Description Molecular determination of 38 allelic variants that determine common and rare red cell antigens plus hemoglobin S status, using multiplex PCR and microarray analysis. Includes DNA extraction and purification.
Turn Around Times 5-7 Business Days
Sample, Packaging & Shipping Requirements 2 EDTA (7 mL) tubes
Form Form BS 313
Laboratory HLA, IRL
Category Platelet Refractory Panel, Platelet Testing
Test Name Platelet Antibody Detection
Description The Capture-P Ready Screen Solid Phase System is designed to detect IgG- HPA and -HLA antibodies. The assay does NOT differentiate between HLA or HPA antibodies. The assay is not designed to detect complement components or antibodies of the IgM or IgA class.
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 3-7 mL EDTA (plasma) or serum tube (no gel separators). Sample must be received in the IRL no later than 30 hrs after collection. Shipped in a container maintaining temperature between 1C - 10C
Form Form BS 313
Laboratory IRL
Category Platelet Refractory Panel, Platelet Testing
Test Name Platelet Crossmatch – SP
Description The Capture-P Solid Phase System is designed to detect IgG HPA and HLA antibodies. The assay is not designed to detect complement components or antibodies of the IgM or IgA class.
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 3-7 mL EDTA (plasma) or serum (not from gel separator tubes). ; Must be received within 30 hours of collection. ; Shipper to maintain temperature between 1C - 10C
Form Form BS 313
Laboratory HLA, IRL
Category Platelet Refractory Panel
Test Name Platelet Refractory Panel
Description Platelet antibody screen and crossmatch, HLA A,B typing, HLA matched platelet donor search, HLA antibody screen (if positive, HLA antibody identification Class I)
Turn Around Times 48 hours
Sample, Packaging & Shipping Requirements Three EDTA whole blood, and 5-7 mL clot (serum) tube (no gel separators). Sample must be received in the IRL no later than 30 hrs after collection. Icteric, hemolyzed and/or lipemic samples interfere with test and should not be tested as per package insert. Shipped in a container maintaining temperature between 1C - 10C
Form Form BS 313, HLA Requisition Form BS 320H
Laboratory IRL
Category Red Cell Serology
Test Name Red Cell Separation
Description Separation of patient red cells from transfused red cells
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Red Cell Treatment – EGA/CHL/DTT
Description Chemical premodification of red cells for testing
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Rh (D) Typing
Description Rh (D) typing of red cells
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Rh Discrepancy
Description Resolution of typing discrepancy
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 2 EDTA tubes; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Rh Phenotype
Description Common Rh antigen phenotyping, excluding Rh (D)
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 EDTA tube; Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Special Serum Studies (0.01 M DTT, others)
Description Selective inactivation of IgM class immunoglobulin
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Special Serum Studies (Neutralization/Inhibition, i.e. Le & P1 substance)
Description Antibody inhibition using blood group substances
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements 1 plain red top and 4 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Thermal Amplitude
Description Determination of optimal temperature of reactivity of cold antibodies
Turn Around Times 24 hours
Sample, Packaging & Shipping Requirements Serum collected and separated at 37 C and 1 EDTA. Please contact the IRL.
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Titration Studies (per titration)
Description Serial dilution of the sample and testing
Turn Around Times NA
Sample, Packaging & Shipping Requirements 1 plain red top and 1 EDTA tubes (No gel separator tubes); Shipped in a container maintaining temperature between 1C - 10 C
Form Form BS 313
Laboratory IRL
Category Red Cell Serology
Test Name Turn Around Times
Description STAT: 8 hours; ASAP: 24 hours; Routine: 1-2 days
Turn Around Times Depends upon request; See TAT description
Sample, Packaging & Shipping Requirements Insufficient sample or incomplete patient information may result in delays
Form NA